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Mild deprotection of the N-tert-butyloxycarbonyl (N-Boc) group using oxalyl chloride
We report a mild method for the selective deprotection of the N-Boc group from a structurally diverse set of compounds, encompassing aliphatic, aromatic, and heterocyclic substrates by using oxalyl chloride in methanol. The reactions take place under room temperature conditions for 1–4 h with yields...
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| Publicado no: | RSC Adv |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810210/ https://ncbi.nlm.nih.gov/pubmed/33456769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ra04110f |
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