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AN EFFICIENT DEPROTECTION OF N-TRIMETHYLSILYLETHOXYMETHYL (SEM) GROUPS FROM DINUCLEOSIDES AND DINUCLEOTIDES

A convenient and efficient method for deprotection of N-(trimethyl)silylethoxymethyl (SEM) groups from thymidine dinucleoside and dinucleotide has been achieved. The SEM groups were easily removed in excellent yields from protected nucleosides, dinucleosides, and dinucleotides.

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Detalhes bibliográficos
Publicado no:Nucleosides Nucleotides Nucleic Acids
Main Authors: Chandra, Tilak, Broderick, William E., Broderick, Joan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331121/
https://ncbi.nlm.nih.gov/pubmed/20391200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257771003612847
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