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Enantioselective total synthesis of (−)-myrifabral A and B

A catalytic enantioselective approach to the Myrioneuron alkaloids (−)-myrifabral A and (−)-myrifabral B is described. The synthesis was enabled by a palladium-catalyzed enantioselective allylic alkylation, that generates the C(10) all-carbon quaternary center. A key N-acyl iminium ion cyclization f...

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Publicat a:Chem Sci
Autors principals: Fulton, Tyler J., Chen, Anthony Y., Bartberger, Michael D., Stoltz, Brian M.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162428/
https://ncbi.nlm.nih.gov/pubmed/34094334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc01141j
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