Two-in-one strategy for fluorene-based spirocycles via Pd(0)-catalyzed spiroannulation of o-iodobiaryls with bromonaphthols

Rapid assembly of fluorene-based spirocycles represents a highly significant but challenging task in organic synthesis. Reported herein is a novel Pd(0)-catalyzed [4+1] spiroannulation of simple o-iodobiaryls with bromonaphthols for the one-step construction of [4,5]-spirofluorenes in high yields wi...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Tan, Bojun, Liu, Long, Zheng, Huayu, Cheng, Tianyi, Zhu, Dianhu, Yang, Xiaofeng, Luan, Xinjun
Format: Artigo
Language:Inglês
Published: The Royal Society of Chemistry 2020
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162402/
https://ncbi.nlm.nih.gov/pubmed/34094284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04386a
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