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Aptamers targeting protein-specific glycosylation in tumor biomarkers: general selection, characterization and structural modeling

Detecting specific protein glycoforms is attracting particular attention due to its potential to improve the performance of current cancer biomarkers. Although natural receptors such as lectins and antibodies have served as powerful tools for the detection of protein-bound glycans, the development o...

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Publicat a:Chem Sci
Autors principals: Díaz-Fernández, Ana, Miranda-Castro, Rebeca, Díaz, Natalia, Suárez, Dimas, de-los-Santos-Álvarez, Noemí, Lobo-Castañón, M. Jesús
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162130/
https://ncbi.nlm.nih.gov/pubmed/34094206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc00209g
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