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Aptamers targeting protein-specific glycosylation in tumor biomarkers: general selection, characterization and structural modeling

Detecting specific protein glycoforms is attracting particular attention due to its potential to improve the performance of current cancer biomarkers. Although natural receptors such as lectins and antibodies have served as powerful tools for the detection of protein-bound glycans, the development o...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Díaz-Fernández, Ana, Miranda-Castro, Rebeca, Díaz, Natalia, Suárez, Dimas, de-los-Santos-Álvarez, Noemí, Lobo-Castañón, M. Jesús
Format: Artigo
Language:Inglês
Published: The Royal Society of Chemistry 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162130/
https://ncbi.nlm.nih.gov/pubmed/34094206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc00209g
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