PLEK2 promotes osteosarcoma tumorigenesis and metastasis by activating the PI3K/AKT signaling pathway

Increasing evidence suggest that pleckstrin-2 (PLEK2) acts as an oncogene in several malignancies. The present study aimed to investigate the effects of PLEK2 on osteosarcoma (OS) tumorigenesis and metastasis. PLEK2 expression in OS was analyzed via bioinformatics, reverse transcription-quantitative...

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Pubblicato in:Oncol Lett
Autori principali: Liu, Yang, Yang, Siting, Wang, Feng, Zhou, Zheng, Xu, Wenjing, Xie, Jingjing, Qiao, Linhui, Gu, Yanglin
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161470/
https://ncbi.nlm.nih.gov/pubmed/34084215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12795
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