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High expression of ID1 facilitates metastasis in human osteosarcoma by regulating the sensitivity of anoikis via PI3K/AKT depended suppression of the intrinsic apoptotic signaling pathway

A lack of understanding of the molecular basis underlying the regulation of metastatic disease and its effective therapy are the primary causes of high mortality in osteosarcoma. Thus, new insights into metastases and novel effective targets for metastatic osteosarcoma are urgently required. Anoikis...

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Detalles Bibliográficos
Publicado en:Am J Transl Res
Main Authors: Zhao, Guo-Sheng, Zhang, Qiao, Cao, Ya, Wang, Yang, Lv, Yang-Fan, Zhang, Zhao-Si, Zhang, Yuan, Tan, Qiu-Lin, Chang, Yu, Quan, Zheng-Xue, Jiang, Dian-Ming, Guo, Qiao-Nan
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511763/
https://ncbi.nlm.nih.gov/pubmed/31105823
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