High expression of ID1 facilitates metastasis in human osteosarcoma by regulating the sensitivity of anoikis via PI3K/AKT depended suppression of the intrinsic apoptotic signaling pathway

A lack of understanding of the molecular basis underlying the regulation of metastatic disease and its effective therapy are the primary causes of high mortality in osteosarcoma. Thus, new insights into metastases and novel effective targets for metastatic osteosarcoma are urgently required. Anoikis...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zhao, Guo-Sheng, Zhang, Qiao, Cao, Ya, Wang, Yang, Lv, Yang-Fan, Zhang, Zhao-Si, Zhang, Yuan, Tan, Qiu-Lin, Chang, Yu, Quan, Zheng-Xue, Jiang, Dian-Ming, Guo, Qiao-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511763/
https://ncbi.nlm.nih.gov/pubmed/31105823
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