APRIL Induces Tumorigenesis and Metastasis of Colorectal Cancer Cells via Activation of the PI3K/Akt Pathway

A proliferation-inducing ligand (APRIL) is highly expressed in colorectal cancer (CRC) tissues and cell lines. However, the biological functions and precise signals elicited by APRIL in CRC have not been fully understood. Here, we used small interfering RNA to selectively deplete APRIL and to determ...

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Detalhes bibliográficos
Main Authors: Wang, Guihua, Wang, Feng, Ding, Weifeng, Wang, Jingchun, Jing, Rongrong, Li, Haiquan, Wang, Xudong, Wang, Yueguo, Ju, Shaoqing, Wang, Huimin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558491/
https://ncbi.nlm.nih.gov/pubmed/23383143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055298
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