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Cyclin-Dependent Kinase Inhibitors in Hematological Malignancies—Current Understanding, (Pre-)Clinical Application and Promising Approaches

SIMPLE SUMMARY: Cyclin-dependent kinases are involved in the regulation of cancer-initiating processes like cell cycle progression, transcription, and DNA repair. In hematological neoplasms, these enzymes are often overexpressed, resulting in increased cell proliferation and cancer progression. Earl...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Richter, Anna, Schoenwaelder, Nina, Sender, Sina, Junghanss, Christian, Maletzki, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161389/
https://ncbi.nlm.nih.gov/pubmed/34065376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102497
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