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Cyclin-dependent kinase inhibitor therapy for hematologic malignancies
INTRODUCTION: Cyclin-dependent kinases (CDKs) regulate cell cycle progression. Certain CDKs (e.g., CDK7, CDK9) also control cellular transcription. Consequently, CDKs represent attractive targets for anti-cancer drug development, as their aberrant expression is common in diverse malignancies, and CD...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4039040/ https://ncbi.nlm.nih.gov/pubmed/23647051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2013.789859 |
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