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The promise of Janus kinase inhibitors in the treatment of hematological malignancies
The Janus kinases (JAK) are a family of kinases that play an essential role in cytokine signaling and are implicated in the pathogenesis of autoimmune diseases and hematological malignancies. As a result, the JAKs have become attractive therapeutic targets. The discovery of a JAK2 point mutation (JA...
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| Pubblicato in: | Cytokine |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5854188/ https://ncbi.nlm.nih.gov/pubmed/28277287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2016.10.012 |
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