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The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis
The pathogenesis of SpA is multifactorial and involves a range of immune cell types and cytokines, many of which utilize Janus kinase (JAK) pathways for signaling. In this review, we summarize the animal and pre-clinical data that have demonstrated the effects of JAK blockade on the underlying molec...
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| Pubblicato in: | Rheumatology (Oxford) |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6343466/ https://ncbi.nlm.nih.gov/pubmed/29618084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/key070 |
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