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The Role of Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy

SIMPLE SUMMARY: Sphingolipids are membrane-associated lipids that are involved in signal transduction pathways regulating cell death, growth, and migration. In cancer cells, sphingolipids regulate pathways relevant to cancer therapy, such as invasion, metastasis, apoptosis, and lethal mitophagy. Not...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sheridan, Megan, Ogretmen, Besim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161379/
https://ncbi.nlm.nih.gov/pubmed/34069611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102475
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