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Ceramide stress in survival versus lethal autophagy paradox: Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
In a recent study, characterization of novel mechanisms that regulate lethal autophagy revealed that C(18)-ceramide stress mediates LC3B-II-ceramide binding on mitochondrial membranes to target autophagosomes for mitophagy induction and tumor suppression.
Wedi'i Gadw mewn:
| Prif Awduron: | , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Landes Bioscience
2013
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552895/ https://ncbi.nlm.nih.gov/pubmed/23182807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22739 |
| Tagiau: |
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