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A practical catalytic reductive amination of carboxylic acids
We report reductive alkylation reactions of amines using carboxylic acids as nominal electrophiles. The two-step reaction exploits the dual reactivity of phenylsilane and involves a silane-mediated amidation followed by a Zn(OAc)(2)-catalyzed amide reduction. The reaction is applicable to a wide ran...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8161228/ https://ncbi.nlm.nih.gov/pubmed/34123174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02271c |
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