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Atom-economic catalytic amide synthesis from amines and carboxylic acids activated in situ with acetylenes

Amide bond-forming reactions are of tremendous significance in synthetic chemistry. Methodological research has, in the past, focused on efficiency and selectivity, and these have reached impressive levels. However, the unacceptable amounts of waste produced have led the ACS GCI Roundtable to label...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Krause, Thilo, Baader, Sabrina, Erb, Benjamin, Gooßen, Lukas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906407/
https://ncbi.nlm.nih.gov/pubmed/27282773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11732
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