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Atom-economic catalytic amide synthesis from amines and carboxylic acids activated in situ with acetylenes

Amide bond-forming reactions are of tremendous significance in synthetic chemistry. Methodological research has, in the past, focused on efficiency and selectivity, and these have reached impressive levels. However, the unacceptable amounts of waste produced have led the ACS GCI Roundtable to label...

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Pubblicato in:Nat Commun
Autori principali: Krause, Thilo, Baader, Sabrina, Erb, Benjamin, Gooßen, Lukas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906407/
https://ncbi.nlm.nih.gov/pubmed/27282773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11732
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