Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication

Human cytomegalovirus (HCMV) is a leading cause of severe diseases in immunocompromised individuals, including AIDS patients and transplant recipients, and in congenitally infected newborns. The utility of available drugs is limited by poor bioavailability, toxicity, and emergence of resistant strai...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Viruses
Päätekijät: Ghassabian, Hanieh, Falchi, Federico, Timmoneri, Martina, Mercorelli, Beatrice, Loregian, Arianna, Palù, Giorgio, Alvisi, Gualtiero
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160850/
https://ncbi.nlm.nih.gov/pubmed/34065234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13050941
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