Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication

Human cytomegalovirus (HCMV) is a leading cause of severe diseases in immunocompromised individuals, including AIDS patients and transplant recipients, and in congenitally infected newborns. The utility of available drugs is limited by poor bioavailability, toxicity, and emergence of resistant strai...

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Vydáno v:Viruses
Hlavní autoři: Ghassabian, Hanieh, Falchi, Federico, Timmoneri, Martina, Mercorelli, Beatrice, Loregian, Arianna, Palù, Giorgio, Alvisi, Gualtiero
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160850/
https://ncbi.nlm.nih.gov/pubmed/34065234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13050941
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