Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia

Neonatal hyperbilirubinemia or jaundice is associated with kernicterus, resulting in permanent neurological damage or even death. Conventional phototherapy does not prevent hyperbilirubinemia or eliminate the need for exchange transfusion. Here we investigated the potential of therapeutic bile acids...

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Publicado no:Sci Rep
Main Authors: van der Schoor, Lori W. E., Verkade, Henkjan J., Bertolini, Anna, de Wit, Sanne, Mennillo, Elvira, Rettenmeier, Eva, Weber, André A., Havinga, Rick, Valášková, Petra, Jašprová, Jana, Struik, Dicky, Bloks, Vincent W., Chen, Shujuan, Schreuder, Andrea B., Vítek, Libor, Tukey, Robert H., Jonker, Johan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160219/
https://ncbi.nlm.nih.gov/pubmed/34045606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90687-5
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