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In silico analysis of BRCA1 and BRCA2 missense variants and the relevance in molecular genetic testing
Over the years since the genetic testing of BRCA1 and BRCA2 has been conducted for research and later introduced into clinical practice, a high number of missense variants have been reported in the literature and deposited in public databases. Polymorphism Phenotyping v2 (PolyPhen-2) and Sorting Int...
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| Publicado no: | Sci Rep |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8160182/ https://ncbi.nlm.nih.gov/pubmed/34045478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88586-w |
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