NAD(+) Repletion Reverses Heart Failure with Preserved Ejection Fraction

RATIONALE: Heart failure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies. We recently demonstrated in mice that a combination of metabolic and hypertensive stress recapitulates key features of human HFpEF. OBJECTIVE: Using this novel preclinical HFp...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Tong, Dan, Schiattarella, Gabriele G., Jiang, Nan, Altamirano, Francisco, Szweda, Pamela A., Elnwasany, Abdallah, Lee, Dong Ik, Yoo, Heesoo, Kass, David A., Szweda, Luke I., Lavandero, Sergio, Verdin, Eric, Gillette, Thomas G., Hill, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159891/
https://ncbi.nlm.nih.gov/pubmed/33882692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.317046
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