NAD(+) Repletion Reverses Heart Failure with Preserved Ejection Fraction

RATIONALE: Heart failure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies. We recently demonstrated in mice that a combination of metabolic and hypertensive stress recapitulates key features of human HFpEF. OBJECTIVE: Using this novel preclinical HFp...

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Publicat a:Circ Res
Autors principals: Tong, Dan, Schiattarella, Gabriele G., Jiang, Nan, Altamirano, Francisco, Szweda, Pamela A., Elnwasany, Abdallah, Lee, Dong Ik, Yoo, Heesoo, Kass, David A., Szweda, Luke I., Lavandero, Sergio, Verdin, Eric, Gillette, Thomas G., Hill, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159891/
https://ncbi.nlm.nih.gov/pubmed/33882692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.317046
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