A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein

Soluble forms of aggregated tau misfolded protein, generally termed oligomers, are considered to be the most toxic species of the different assembly states that are the pathological components of neurodegenerative disorders. Therefore, a critical biomedical need exists for imaging probes that can id...

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Bibliografische gegevens
Gepubliceerd in:Chem Sci
Hoofdauteurs: Zhao, Yanyan, Tietz, Ole, Kuan, Wei-Li, Haji-Dheere, Abdul K., Thompson, Stephen, Vallin, Benjamin, Ronchi, Elisabetta, Tóth, Gergely, Klenerman, David, Aigbirhio, Franklin I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society of Chemistry 2020
Onderwerpen:
Chemistry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159431/
https://ncbi.nlm.nih.gov/pubmed/34122933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05620c
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