A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein

Soluble forms of aggregated tau misfolded protein, generally termed oligomers, are considered to be the most toxic species of the different assembly states that are the pathological components of neurodegenerative disorders. Therefore, a critical biomedical need exists for imaging probes that can id...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Zhao, Yanyan, Tietz, Ole, Kuan, Wei-Li, Haji-Dheere, Abdul K., Thompson, Stephen, Vallin, Benjamin, Ronchi, Elisabetta, Tóth, Gergely, Klenerman, David, Aigbirhio, Franklin I.
Format: Artigo
Language:Inglês
Published: The Royal Society of Chemistry 2020
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159431/
https://ncbi.nlm.nih.gov/pubmed/34122933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05620c
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