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Silanol: a bifunctional group for peptide synthesis and late-stage functionalization
Chemical modification of a specific amino acid residue on peptides represents an efficient strategy to improve their pharmacokinetics and facilitates the potential to achieve post-synthetic diversification of peptides. Herein, we reported the first Pd-catalyzed late-stage ortho-olefination of Tyr re...
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| Udgivet i: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society of Chemistry
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8159358/ https://ncbi.nlm.nih.gov/pubmed/34094099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02439b |
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