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Real-World Use of Azathioprine Metabolites Changes Clinical Management of Inflammatory Bowel Disease
BACKGROUND: Thiopurines such as 6-mercaptopurine and azathioprine have complex metabolism, resulting in significant inter-individual differences in clinical efficacy and risk of drug toxicity, making conventional weight-based dosing inaccurate and potentially unsafe. Therapeutic drug monitoring (TDM...
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| Udgivet i: | J Can Assoc Gastroenterol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8158651/ https://ncbi.nlm.nih.gov/pubmed/34056527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwaa005 |
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