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Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease

The thiopurine drugs, 6-mercaptopurine (6-MP) and azathioprine, are efficacious in the arsenal of inflammatory bowel disease (IBD) therapy. Previous reports indicate that 6-thioguanine nucleotide (6-TGN) levels correlate with therapeutic efficacy, whereas high 6-methylmercaptopurine (6-MMP) levels a...

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Detalhes bibliográficos
Main Authors: Bradford, Kara, Shih, David Q
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208360/
https://ncbi.nlm.nih.gov/pubmed/22072847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i37.4166
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