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Ensembles in solution as a new paradigm for antibody structure prediction and design

The rise of antibodies as a promising and rapidly growing class of biotherapeutic proteins has motivated numerous studies to characterize and understand antibody structures. In the past decades, the number of antibody crystal structures increased substantially, which revolutionized the atomistic und...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:MAbs
Hauptverfasser: Fernández-Quintero, Monica L., Georges, Guy, Varga, Janos M., Liedl, Klaus R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158028/
https://ncbi.nlm.nih.gov/pubmed/34030577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2021.1923122
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