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Hyperoxia causes senescence and increases glycolysis in cultured lung epithelial cells

Supplemental oxygen and mechanical ventilation commonly used in premature infants may lead to chronic lung disease of prematurity, which is characterized by arrested alveolar development and dysmorphic vascular development. Hyperoxia is also known to dysregulate p53, senescence, and metabolism. Howe...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Scaffa, Alejandro M., Peterson, Abigail L., Carr, Jennifer F., Garcia, David, Yao, Hongwei, Dennery, Phyllis A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157762/
https://ncbi.nlm.nih.gov/pubmed/34042288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14839
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