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Hyperoxia causes senescence and increases glycolysis in cultured lung epithelial cells

Supplemental oxygen and mechanical ventilation commonly used in premature infants may lead to chronic lung disease of prematurity, which is characterized by arrested alveolar development and dysmorphic vascular development. Hyperoxia is also known to dysregulate p53, senescence, and metabolism. Howe...

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Détails bibliographiques
Publié dans:Physiol Rep
Auteurs principaux: Scaffa, Alejandro M., Peterson, Abigail L., Carr, Jennifer F., Garcia, David, Yao, Hongwei, Dennery, Phyllis A.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157762/
https://ncbi.nlm.nih.gov/pubmed/34042288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14839
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