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Hyperoxia causes senescence and increases glycolysis in cultured lung epithelial cells

Supplemental oxygen and mechanical ventilation commonly used in premature infants may lead to chronic lung disease of prematurity, which is characterized by arrested alveolar development and dysmorphic vascular development. Hyperoxia is also known to dysregulate p53, senescence, and metabolism. Howe...

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Vydáno v:Physiol Rep
Hlavní autoři: Scaffa, Alejandro M., Peterson, Abigail L., Carr, Jennifer F., Garcia, David, Yao, Hongwei, Dennery, Phyllis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157762/
https://ncbi.nlm.nih.gov/pubmed/34042288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14839
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