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Probing enzymatic activity – a radical approach

Deubiquitinating enzymes (DUBs) are known to have numerous important interactions with the ubiquitin cascade and their dysregulation is associated with several diseases, including cancer and neurodegeneration. They are an important class of enzyme, and activity-based probes have been developed as an...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Taylor, Neil C., Hessman, Gary, Kramer, Holger B., McGouran, Joanna F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157568/
https://ncbi.nlm.nih.gov/pubmed/34122797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05258e
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