Deubiquitinating Enzyme Specificity for Ubiquitin Chain Topology Profiled by Di-Ubiquitin Activity Probes

Posttranslational modification with ubiquitin (Ub) controls many cellular processes, and aberrant ubiquitination can contribute to cancer, immunopathology, and neurodegeneration. The versatility arises from the ability of Ub to form polymer chains with eight distinct linkages via lysine side chains...

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Main Authors: McGouran, Joanna F., Gaertner, Selina R., Altun, Mikael, Kramer, Holger B., Kessler, Benedikt M.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899023/
https://ncbi.nlm.nih.gov/pubmed/24290882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.10.012
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