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PDGF-BB regulates the transformation of fibroblasts into cancer-associated fibroblasts via the lncRNA LURAP1L-AS1/LURAP1L/IKK/IκB/NF-κB signaling pathway

The most abundant cells in the tumor microenvironment are cancer-associated fibroblasts (CAFs). They play an important role in oral squamous cell carcinoma (OSCC) angiogenesis, invasion and metastasis. Platelet-derived growth factor (PDGF)-BB has an obvious regulating effect on the formation of CAFs...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Ren, Xiaobin, Li, Lei, Wu, Jianhua, Lin, Ken, He, Yongwen, Bian, Li
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157341/
https://ncbi.nlm.nih.gov/pubmed/34079593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12798
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