Loading...

Characterization and Optimization of Benzimidazopyrimidine and Pyridoimidazopyridine Derivatives as Tau-SPECT Probes

[Image: see text] The accumulation of hyperphosphorylated tau protein in the brain is regarded as one of the hallmarks of Alzheimer’s disease (AD). In vivo imaging of tau aggregates is helpful for diagnosis and monitoring of the progression of AD. In this study, we designed and synthesized novel rad...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:ACS Med Chem Lett
Main Authors: Watanabe, Hiroyuki, Kishimoto, Takeaki, Kaide, Sho, Tarumizu, Yuta, Tatsumi, Haruka, Iikuni, Shimpei, Ono, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155298/
https://ncbi.nlm.nih.gov/pubmed/34055229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.1c00071
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!