Wordt geladen...

Structure–Activity Relationships of Radioiodinated 6,5,6-Tricyclic Compounds for the Development of Tau Imaging Probes

[Image: see text] Tau aggregate, which is the main component of the neurofibrillary tangle, is an attractive imaging target for diagnosing and monitoring the progression of Alzheimer’s disease (AD). In this study, we designed and synthesized six radioiodinated 6,5,6-tricyclic compounds to explore no...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:ACS Med Chem Lett
Hoofdauteurs: Watanabe, Hiroyuki, Tatsumi, Haruka, Kaide, Sho, Shimizu, Yoichi, Iikuni, Shimpei, Ono, Masahiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2020
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025389/
https://ncbi.nlm.nih.gov/pubmed/32071677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00456
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!