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Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease

Sickle cell disease (SCD) is one of the most common inherited single gene disorders. Polymerisation of sickle hemoglobin results in erythrocytes that are inflexible and adherent, leading to coagulation, vascular and cellular activation and resultant blood vessel blockage. Previous studies have obser...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Smith, Rachel A., Mankelow, Tosti J., Drizou, Despoina, Bullock, Thomas, Latham, Tom, Trompeter, Sara, Blair, Allison, Anstee, David J.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155063/
https://ncbi.nlm.nih.gov/pubmed/34040079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90477-z
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