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Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease

Sickle cell disease (SCD) is one of the most common inherited single gene disorders. Polymerisation of sickle hemoglobin results in erythrocytes that are inflexible and adherent, leading to coagulation, vascular and cellular activation and resultant blood vessel blockage. Previous studies have obser...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Smith, Rachel A., Mankelow, Tosti J., Drizou, Despoina, Bullock, Thomas, Latham, Tom, Trompeter, Sara, Blair, Allison, Anstee, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155063/
https://ncbi.nlm.nih.gov/pubmed/34040079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90477-z
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