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Characterization of the Hypercoagulable State in Patients with Sickle Cell Disease

BACKGROUND: The pathophysiology of sickle cell disease (SCD) is complex, with increasing evidence of a pronounced prothrombotic state. OBJECTIVE: We investigated thrombin generation in SCD utilizing calibrated automated thrombography (CAT) and Ddimer, with subsequent correlation to clinical disease....

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Autors principals: Shah, Nirmish, Thornburg, Courtney, Telen, Marilyn J., Ortel, Thomas L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474885/
https://ncbi.nlm.nih.gov/pubmed/22959127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2012.08.307
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