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Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations

The effect of scheduling of targeted therapy combinations on drug resistance is underexplored in triple-negative breast cancer (TNBC). TNBC constitutes heterogeneous cancer cell populations the composition of which can change dynamically during treatment resulting in the selection of resistant clone...

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Détails bibliographiques
Publié dans:NPJ Breast Cancer
Auteurs principaux: Patwardhan, Gauri A., Marczyk, Michal, Wali, Vikram B., Stern, David F., Pusztai, Lajos, Hatzis, Christos
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154902/
https://ncbi.nlm.nih.gov/pubmed/34040000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-021-00270-4
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