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Potential impacts of the cardiac troponin I mobile domain on myofilament activation and relaxation
The cardiac thin filament is regulated in a Ca(2+)-dependent manner through conformational changes of troponin and tropomyosin (Tm). It has been generally understood that under conditions of low Ca(2+) the inhibitory peptide domain (IP) of troponin I (TnI) binds to actin and holds Tm over the myosin...
Gorde:
| Argitaratua izan da: | J Mol Cell Cardiol |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8154642/ https://ncbi.nlm.nih.gov/pubmed/33647310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2021.02.012 |
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