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Improved Skin Permeability after Topical Treatment with Serine Protease: Probing the Penetration of Rapamycin by Scanning Transmission X-ray Microscopy

[Image: see text] Drug penetration in human skin ex vivo following a modification of skin barrier permeability is systematically investigated by scanning transmission X-ray microscopy. Element-selective excitation is used in the O 1s regime for probing quantitatively the penetration of topically app...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Germer, Gregor, Ohigashi, Takuji, Yuzawa, Hayato, Kosugi, Nobuhiro, Flesch, Roman, Rancan, Fiorenza, Vogt, Annika, Rühl, Eckart
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154144/
https://ncbi.nlm.nih.gov/pubmed/34056375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c01058
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