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Modeling of Drug Diffusion Based on Concentration Profiles in Healthy and Damaged Human Skin
Based on experimental drug concentration profiles in healthy as well as tape-stripped ex vivo human skin, we model the penetration of the antiinflammatory drug dexamethasone into the skin layers by the one-dimensional generalized diffusion equation. We estimate the position-dependent free-energy and...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6732523/ https://ncbi.nlm.nih.gov/pubmed/31400921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.027 |
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