Kinetics and Optimization of the Lysine-Isopeptide Bond Forming Sortase Enzyme from Corynebacterium diphtheriae

Site-specifically modified protein bioconjugates have important applications in biology, chemistry and medicine. Functionalizing specific protein side chains with enzymes using mild reaction conditions is of significant interest, but remains challenging. Recently, the lysine-isopeptide bond forming...

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Vydáno v:Bioconjug Chem
Hlavní autoři: Sue, Christopher K., McConnell, Scott A., Ellis-Guardiola, Ken, Muroski, John, McAllister, Rachel A., Yu, Justin, Alvarez, Ana I., Chang, Chungyu, Ogorzalek Loo, Rachel R., Loo, Joseph A., Ton-That, Hung, Clubb, Robert T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153732/
https://ncbi.nlm.nih.gov/pubmed/32396336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.0c00163
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