Oxygen-Mediated Suppression of CD8+ T Cell Proliferation by Macrophages: Role of Pharmacological Inhibitors of HIF Degradation

Myeloid cell interactions with cells of the adaptive immune system are an essential aspect of immunity. A key aspect of that interrelationship is its modulation by the microenvironment. Oxygen is known to influence myelosuppression of T cell activation in part via the Hypoxia inducible (HIF) transcr...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gojkovic, Milos, Cunha, Pedro P., Darmasaputra, Gabriella S., Barbieri, Laura, Rundqvist, Helene, Veliça, Pedro, Johnson, Randall S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153186/
https://ncbi.nlm.nih.gov/pubmed/34054802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.633586
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