Involvement of PI3K Pathway in Glioma Cell Resistance to Temozolomide Treatment

The aim of the study was to investigate the anticancer potential of LY294002 (PI3K inhibitor) and temozolomide using glioblastoma multiforme (T98G) and anaplastic astrocytoma (MOGGCCM) cells. Apoptosis, autophagy, necrosis, and granules in the cytoplasm were identified microscopically (fluorescence...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Zając, Adrian, Sumorek-Wiadro, Joanna, Langner, Ewa, Wertel, Iwona, Maciejczyk, Aleksandra, Pawlikowska-Pawlęga, Bożena, Pawelec, Jarosław, Wasiak, Magdalena, Hułas-Stasiak, Monika, Bądziul, Dorota, Rzeski, Wojciech, Reichert, Michał, Jakubowicz-Gil, Joanna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152763/
https://ncbi.nlm.nih.gov/pubmed/34068110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105155
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