Involvement of PI3K Pathway in Glioma Cell Resistance to Temozolomide Treatment

The aim of the study was to investigate the anticancer potential of LY294002 (PI3K inhibitor) and temozolomide using glioblastoma multiforme (T98G) and anaplastic astrocytoma (MOGGCCM) cells. Apoptosis, autophagy, necrosis, and granules in the cytoplasm were identified microscopically (fluorescence...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Zając, Adrian, Sumorek-Wiadro, Joanna, Langner, Ewa, Wertel, Iwona, Maciejczyk, Aleksandra, Pawlikowska-Pawlęga, Bożena, Pawelec, Jarosław, Wasiak, Magdalena, Hułas-Stasiak, Monika, Bądziul, Dorota, Rzeski, Wojciech, Reichert, Michał, Jakubowicz-Gil, Joanna
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152763/
https://ncbi.nlm.nih.gov/pubmed/34068110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105155
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