Involvement of PI3K Pathway in Glioma Cell Resistance to Temozolomide Treatment

The aim of the study was to investigate the anticancer potential of LY294002 (PI3K inhibitor) and temozolomide using glioblastoma multiforme (T98G) and anaplastic astrocytoma (MOGGCCM) cells. Apoptosis, autophagy, necrosis, and granules in the cytoplasm were identified microscopically (fluorescence...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Zając, Adrian, Sumorek-Wiadro, Joanna, Langner, Ewa, Wertel, Iwona, Maciejczyk, Aleksandra, Pawlikowska-Pawlęga, Bożena, Pawelec, Jarosław, Wasiak, Magdalena, Hułas-Stasiak, Monika, Bądziul, Dorota, Rzeski, Wojciech, Reichert, Michał, Jakubowicz-Gil, Joanna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152763/
https://ncbi.nlm.nih.gov/pubmed/34068110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105155
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