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A Universal CAR-NK Cell Targeting Various Epitopes of HIV-1 gp160

Engineering T cells and natural killer (NK) cells with anti-HIV chimeric antigen receptors (CAR) has emerged as a promising strategy to eradicate HIV-infected cells. However, current anti-HIV CARs are limited by targeting a single epitope of the HIV envelope glycoprotein gp160, which cannot counter...

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Pubblicato in:ACS Chem Biol
Autori principali: Lim, Rebecca M., Rong, Liang, Zhen, Anjie, Xie, Jianming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152219/
https://ncbi.nlm.nih.gov/pubmed/32667183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00537
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