Design and In Vivo Characterization of Immunoconjugates Targeting HIV gp160

The envelope (Env) glycoprotein of HIV is expressed on the surface of productively infected cells and can be used as a target for cytotoxic immunoconjugates (ICs), in which cell-killing moieties, including toxins, drugs, or radionuclides, are chemically or genetically linked to monoclonal antibodies...

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發表在:J Virol
Main Authors: Pincus, Seth H., Song, Kejing, Maresh, Grace A., Frank, Anderson, Worthylake, David, Chung, Hye-Kyung, Polacino, Patricia, Hamer, Dean H., Coyne, Cody P., Rosenblum, Michael G., Marks, John W., Chen, Gang, Weiss, Deborah, Ghetie, Victor, Vitetta, Ellen S., Robinson, James E., Hu, Shiu-Lok
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2017
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244325/
https://ncbi.nlm.nih.gov/pubmed/27795412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01360-16
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