Design and In Vivo Characterization of Immunoconjugates Targeting HIV gp160

The envelope (Env) glycoprotein of HIV is expressed on the surface of productively infected cells and can be used as a target for cytotoxic immunoconjugates (ICs), in which cell-killing moieties, including toxins, drugs, or radionuclides, are chemically or genetically linked to monoclonal antibodies...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pincus, Seth H., Song, Kejing, Maresh, Grace A., Frank, Anderson, Worthylake, David, Chung, Hye-Kyung, Polacino, Patricia, Hamer, Dean H., Coyne, Cody P., Rosenblum, Michael G., Marks, John W., Chen, Gang, Weiss, Deborah, Ghetie, Victor, Vitetta, Ellen S., Robinson, James E., Hu, Shiu-Lok
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244325/
https://ncbi.nlm.nih.gov/pubmed/27795412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01360-16
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